DSpace Repository :: Browsing by Author "Westenberg, Michel A."

Browsing by Author "Westenberg, Michel A."

Now showing 1 - 5 of 5

GLANCE: Visual Analytics for Monitoring Glaucoma Progression
(The Eurographics Association, 2020) Brandt, Astrid van den; Christopher, Mark; Zangwill, Linda M.; Rezapour, Jasmin; Bowd, Christopher; Baxter, Sally L.; Welsbie, Derek S.; Camp, Andrew; Moghimi, Sasan; Do, Jiun L.; Weinreb, Robert N.; Snijders, Chris C. P.; Westenberg, Michel A.; Kozlíková, Barbora and Krone, Michael and Smit, Noeska and Nieselt, Kay and Raidou, Renata Georgia
Deep learning is increasingly used in the field of glaucoma research. Although deep learning models can achieve high accuracy, issues with trust, interpretability, and practical utility form barriers to adoption in clinical practice. In this study, we explore whether and how visualizations of deep learning-based measurements can be used for glaucoma management in the clinic. Through iterative design sessions with ophthalmologists, vision researchers, and manufacturers of optical coherence tomography (OCT) instruments, we distilled four main tasks, and designed a visualization tool that incorporates a visual field (VF) prediction model to provide clinical decision support in managing glaucoma progression. The tasks are: (1) assess reliability of a prediction, (2) understand why the model made a prediction, (3) alert to features that are relevant, and (4) guide future scheduling of VFs. Our approach is novel in that it considers utility of the system in a clinical context where time is limited. With use cases and a pilot user study, we demonstrate that our approach can aid clinicians in clinical management decisions and obtain appropriate trust in the system. Taken together, our work shows how visual explanations of automated methods can augment clinicians' knowledge and calibrate their trust in DL-based measurements during clinical decision making.
HIFUpm: a Visual Environment to Plan and Monitor High Intensity Focused Ultrasound Treatments
(The Eurographics Association, 2019) Modena, Daniela; Bassano, Davide; Elevelt, Aaldert; Baragona, Marco; Hilbers, Peter A. J.; Westenberg, Michel A.; Kozlíková, Barbora and Linsen, Lars and Vázquez, Pere-Pau and Lawonn, Kai and Raidou, Renata Georgia
High Intensity Focused Ultrasound (HIFU) is a non invasive therapeutic method, which has been a subject of interest for the treatment of various kinds of tumors. Despite the numerous advantages, HIFU techniques do not reach the high delivery precision like other therapies (e.g., radiotherapy). For this reason, a correct therapy planning and monitoring in HIFU treatments remains a challenge. We propose HIFUpm, a visual analytics approach which enables the visualization of the HIFU simulation results, while guiding the user in the evaluation of the procedure. We illustrate the use of HIFUpm for an ablative treatment of an osteoid osteoma. This use case demonstrates that HIFUpm provides a flexible visual environment to plan and monitor HIFU procedures.
PerSleep: A Visual Analytics Approach for Performance Assessment of Sleep Staging Models
(The Eurographics Association, 2021) Garcia Caballero, Humberto S.; Corvò, Alberto; Meulen, Fokke van; Fonseca, Pedro; Overeem, Sebasitaan; Wijk, Jarke J. van; Westenberg, Michel A.; Oeltze-Jafra, Steffen and Smit, Noeska N. and Sommer, Björn and Nieselt, Kay and Schultz, Thomas
Machine learning is becoming increasingly popular in the medical domain. In the near future, clinicians expect predictive models to support daily tasks such as diagnosis and prognostic analysis. For this reason, it is utterly important to evaluate and compare the performance of such models so that clinicians can safely rely on them. In this paper, we focus on sleep staging wherein machine learning models can be used to automate or support sleep scoring. Evaluation of these models is complex because sleep is a natural process, which varies among patients. For adoption in clinical routine, it is important to understand how the models perform for different groups of patients. Moreover, models can be trained to recognize different characteristics in the data, and model developers need to understand why and how performance of the different models varies. To address these challenges, we present a visual analytics approach to evaluate the performance of predictive models on sleep staging and to help experts better understand these models with respect to patient data (e.g., conditions, medication, etc.). We illustrate the effectiveness of our approach by comparing multiple models trained on real-world sleep staging data with experts.
Visual Analytics in Digital Pathology: Challenges and Opportunities
(The Eurographics Association, 2019) Corvò, Alberto; Westenberg, Michel A.; Wimberger-Friedl, Reinhold; Fromme, Stephan; Peeters, Michel M. R.; Driel, Marc A. van; Wijk, Jarke J. van; Kozlíková, Barbora and Linsen, Lars and Vázquez, Pere-Pau and Lawonn, Kai and Raidou, Renata Georgia
The advances in high-throughput digitization, digital pathology systems, and quantitative image analysis opened new horizons in pathology. The diagnostic work of the pathologists and their role is likely to be augmented with computer-assistance and more quantitative information at hand. The recent success of artificial intelligence (AI) and computer vision methods demonstrated that in the coming years machines will support pathologists in typically tedious and highly subjective tasks and also in better patient stratification. In spite of clear future improvements in the diagnostic workflow, questions on how to effectively support the pathologists and how to integrate current data sources and quantitative information still persist. In this context, Visual Analytics (VA) - as the discipline that aids users to solve complex problems with an interactive and visual approach - can play a vital role to support the cognitive skills of pathologists and the large volumes of data available. To identify the main opportunities to employ VA in digital pathology systems, we conducted a survey with 20 pathologists to characterize the diagnostic practice and needs from a user perspective. From our findings, we discuss how VA can leverage quantitative image data to empower pathologists with new advanced digital pathology systems.
Visual Analytics in Histopathology Diagnostics: a Protocol-Based Approach
(The Eurographics Association, 2018) Corvò, Alberto; Westenberg, Michel A.; Driel, Marc A. van; Wijk, Jarke J.van; Puig Puig, Anna and Schultz, Thomas and Vilanova, Anna and Hotz, Ingrid and Kozlikova, Barbora and Vázquez, Pere-Pau
Computer-Aided-Diagnosis (CAD) systems supporting the diagnostic process are widespread in radiology. Digital Pathology is still behind in the introduction of such solutions. Several studies investigated pathologists' behavior but only a few aimed to improve the diagnostic and report process with novel applications. In this work we designed and implemented a first protocol-based CAD viewer supported by visual analytics. The system targets the optimization of the diagnostic workflow in breast cancer diagnosis by means of three image analysis features that belong to the standard grading system (Nottingham Histologic Grade). A pathologist's routine was tracked during the examination of breast cancer tissue slides and diagnostic traces were analyzed from a qualitative perspective. Accordingly, a set of generic requirements was elicited to define the design and the implementation of the CAD-Viewer. A first qualitative evaluation conducted with five pathologists shows that the interface suffices the diagnostic workflow and diminishes the manual effort. We present promising evidence of the usefulness of our CAD-viewer and opportunities for its extension and integration in clinical practice. As a conclusion, the findings demonstrate that it is feasibile to optimize the Nottingham Grading workflow and, generally, the histological diagnosis by integrating computational pathology data with visual analytics techniques.

Browsing by Author "Westenberg, Michel A."

Results Per Page

Sort Options