DimSUM: Dimension and Scale Unifying Map for Visual Abstraction of DNA Origami Structures

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dc.contributor.authorMiao, Haichaoen_US
dc.contributor.authorLlano, Elisa Deen_US
dc.contributor.authorIsenberg, Tobiasen_US
dc.contributor.authorGröller, Eduarden_US
dc.contributor.authorBarišic, Ivanen_US
dc.contributor.authorViola, Ivanen_US
dc.contributor.editorJeffrey Heer and Heike Leitte and Timo Ropinskien_US
dc.date.accessioned2018-06-02T18:08:48Z
dc.date.available2018-06-02T18:08:48Z
dc.date.issued2018
dc.description.abstractWe present a novel visualization concept for DNA origami structures that integrates a multitude of representations into a Dimension and Scale Unifying Map (DimSUM). This novel abstraction map provides means to analyze, smoothly transition between, and interact with many visual representations of the DNA origami structures in an effective way that was not possible before. DNA origami structures are nanoscale objects, which are challenging to model in silico. In our holistic approach we seamlessly combine three-dimensional realistic shape models, two-dimensional diagrammatic representations, and ordered alignments in one-dimensional arrangements, with semantic transitions across many scales. To navigate through this large, two-dimensional abstraction map we highlight locations that users frequently visit for certain tasks and datasets. Particularly interesting viewpoints can be explicitly saved to optimize the workflow. We have developed DimSUM together with domain scientists specialized in DNA nanotechnology. In the paper we discuss our design decisions for both the visualization and the interaction techniques. We demonstrate two practical use cases in which our approach increases the specialists' understanding and improves their effectiveness in the analysis. Finally, we discuss the implications of our concept for the use of controlled abstraction in visualization in general.en_US
dc.description.number3
dc.description.sectionheadersBiological Visualization
dc.description.seriesinformationComputer Graphics Forum
dc.description.volume37
dc.identifier.doi10.1111/cgf.13429
dc.identifier.issn1467-8659
dc.identifier.pages403-413
dc.identifier.urihttps://doi.org/10.1111/cgf.13429
dc.identifier.urihttps://diglib.eg.org:443/handle/10.1111/cgf13429
dc.publisherThe Eurographics Association and John Wiley & Sons Ltd.en_US
dc.subjectHuman centered computing
dc.subjectScientific visualization
dc.subjectVisualization theory
dc.subjectconcepts and paradigms
dc.subjectApplied computing
dc.subjectComputational biology
dc.titleDimSUM: Dimension and Scale Unifying Map for Visual Abstraction of DNA Origami Structuresen_US
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