CT Late Enhancement Segmentation for the Combined Analysis of Coronary Arteries and Myocardial Viability

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dc.contributor.authorHennemuth, Anjaen_US
dc.contributor.authorMahnken, Andreasen_US
dc.contributor.authorKühnel, Carolineen_US
dc.contributor.authorOeltze, Steffenen_US
dc.contributor.authorPeitgen, Heinz-Ottoen_US
dc.contributor.editorCharl Botha and Gordon Kindlmann and Wiro Niessen and Bernhard Preimen_US
dc.date.accessioned2014-01-29T17:02:03Z
dc.date.available2014-01-29T17:02:03Z
dc.date.issued2008en_US
dc.description.abstractNon-invasive imaging techniques become more and more important as diagnostic tools for the assessment of coronary heart disease (CHD). While CT is widely applied for the inspection of the coronary arteries, the state of myocardial tissue is normally analyzed with MRI or nuclear imaging methods such as PET or SPECT. The effect of late enhancement, the accumulation of contrast agent in defective tissue, is used to assess tissue viability with MR imaging. Studies have shown, that this effect can be observed for iodine based contrast agents, which are used for CT coronary artery imaging, as well. Thus the goal of this work is the development of segmentation and visualization methods, which allow a combined inspection of the coronary arteries and the viability of the corresponding myocardial tissue. We therefore present a new segmentation method for the analysis of CT late enhancement images and the integration with methods for the inspection of the coronary arteries. In preliminary tests by a radiologist, the methods are applied to 4 datasets to compare the segmentation with the reference method, test the combined inspection for data with a known relation between infarction and supplying artery and test the general applicability to patient data. The preliminary results are promising, and further studies will focus on the evaluation of the segmentation method as well as on the clinical benefit through the combined analysis.en_US
dc.description.seriesinformationEurographics Workshop on Visual Computing for Biomedicineen_US
dc.identifier.isbn978-3-905674-13-2en_US
dc.identifier.issn2070-5786en_US
dc.identifier.urihttps://doi.org/10.2312/VCBM/VCBM08/001-009en_US
dc.publisherThe Eurographics Associationen_US
dc.subjectCategories and Subject Descriptors (according to ACM CCS): I.3.3 [Computer Graphics]: Image processing softwareen_US
dc.titleCT Late Enhancement Segmentation for the Combined Analysis of Coronary Arteries and Myocardial Viabilityen_US
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VCBM 08: Eurographics Workshop on Visual Computing for Biomedicine